GLP-1 Medication Comparison Chart
Compare Ozempic, Wegovy, Zepbound, Foundayo, Mounjaro, and Rybelsus side-by-side — dosing, weight loss, cost, insurance, and more.
| Drug Name | Active Ingredient | Type | Frequency | Max Dose | FDA Approval | Avg Weight Loss | Insurance | Self-Pay/mo | Key Trial | Food Restrictions |
|---|---|---|---|---|---|---|---|---|---|---|
| Ozempic | Semaglutide | Injection | Weekly | 2 mg | Diabetes (T2D) | ~11% | Broad | $900–$1,100 | SUSTAIN | None |
| Wegovy (inj) | Semaglutide | Injection | Weekly | 2.4 mg | Weight loss | ~15% | Growing | $1,300–$1,400 | STEP | None |
| Wegovy (pill) | Semaglutide | Pill | Daily | 25 mg | Weight loss | ~13.6% | Pending | TBD | OASIS | 30 min before food w/ ≤4 oz water |
| Foundayo | Tirzepatide | Pill | Daily | TBD | Weight loss | ~20% | Pending | TBD | SURMOUNT-1 (oral) | 30 min before food w/ ≤4 oz water |
| Zepbound | Tirzepatide | Injection | Weekly | 15 mg | Weight loss | ~21% | Growing | $1,000–$1,100 | SURMOUNT | None |
| Mounjaro | Tirzepatide | Injection | Weekly | 15 mg | Diabetes (T2D) | ~21% | Broad | $1,000–$1,100 | SURPASS | None |
| Rybelsus | Semaglutide | Pill | Daily | 14 mg | Diabetes (T2D) | ~4% | Moderate | $900–$1,000 | PIONEER | 30 min before food w/ ≤4 oz water |
Scroll horizontally on mobile to view all columns. Data sourced from FDA labels and published clinical trials.
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Ready to Get Started? Compare GLP-1 Providers
MEDVi
Best ValueGLP-1 weight loss program — take a 60-second quiz to see if you qualify. Compounded semaglutide and tirzepatide from $99/month with provider support.
Get StartedStrut Health
Free ShippingGLP-1 weight loss prescriptions from licensed U.S. providers. Free shipping on all orders, cancel anytime.
Get StartedDudeMeds
Budget FriendlyBudget-friendly GLP-1 weight loss program. Get prescribed by a licensed provider with no insurance required.
Get StartedMedical Disclaimer: This tool is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting, stopping, or switching any medication. Individual results vary. Insurance coverage and self-pay pricing are approximate and subject to change.