GLP-1 Medications: Complete Guide
Every GLP-1 medication available in 2026 — FDA-approved brand names and compounded alternatives. Click any medication for detailed dosing, side effects, clinical trial results, and cost information.
FDA-Approved Medications
orforglipron · Eli Lilly
Weight loss: 12.4% (completers) / 11.2% (ITT) (ATTAIN-1 (17.2mg approved dose))
semaglutide · Novo Nordisk
Weight loss: ~15% (SUSTAIN 1-10 / STEP (off-label))
semaglutide · Novo Nordisk
Weight loss: ~14.9% (STEP 1)
semaglutide (oral) · Novo Nordisk
Weight loss: ~16.6% (OASIS 4)
tirzepatide · Eli Lilly
Weight loss: ~22.5% (SURMOUNT-1)
tirzepatide · Eli Lilly
Weight loss: ~9.5% (SURPASS-1)
semaglutide (oral) · Novo Nordisk
Weight loss: ~4-5% (PIONEER trials)
Compounded (Not FDA-Approved)
⚠️ Important: Compounded GLP-1 medications are not FDA-approved. Quality varies by pharmacy, and FDA enforcement is increasing. Consider transitioning to an FDA-approved alternative.
Medical Disclaimer: This information is for educational purposes only and does not constitute medical advice. All clinical data referenced comes from published clinical trials and FDA prescribing information. Always consult your healthcare provider before starting, stopping, or switching any medication. Individual results may vary.