Foundayo (orforglipron) became available by prescription on April 1, 2026, and LillyDirect began shipping to patients on April 6. If you are interested in starting Foundayo, the good news is that the prescription process is straightforward — no specialist is required, and telehealth providers can often prescribe it the same day. This guide walks through every step, from eligibility to filling your first prescription.
Who Qualifies for Foundayo?
Foundayo is FDA-approved for chronic weight management in adults who meet one of the following criteria:
- BMI ≥30 (obesity), OR
- BMI ≥27 (overweight) with at least one weight-related comorbidity
Qualifying comorbidities include:
- Hypertension (high blood pressure)
- Type 2 diabetes
- Dyslipidemia (high cholesterol or triglycerides)
- Obstructive sleep apnea
- Cardiovascular disease
- Osteoarthritis
Foundayo is intended for use alongside a reduced-calorie diet and increased physical activity. It is prescribed as a once-daily oral tablet — no injections needed.
Option 1: Your Primary Care Doctor
Most primary care physicians (PCPs) are qualified to prescribe Foundayo. Since it is a non-controlled oral medication, there are no DEA scheduling requirements and no specialist referral is needed. If you have an established relationship with your PCP and they are familiar with GLP-1 receptor agonists, this is often the simplest pathway. Your PCP can also handle prior authorization submissions if you are using insurance.
If your PCP is unfamiliar with Foundayo specifically, bring printed prescribing information from foundayo.lilly.com or mention that it is the first oral nonpeptide GLP-1 for weight management. Most PCPs who prescribe Wegovy or Ozempic will be comfortable with Foundayo.
Option 2: Endocrinologist or Obesity Medicine Specialist
For patients with complex medical histories — uncontrolled type 2 diabetes, severe insulin resistance, history of bariatric surgery, or multiple metabolic conditions — a specialist referral may be beneficial. Endocrinologists and board-certified obesity medicine physicians have advanced training in GLP-1 pharmacology and can tailor dosing and monitoring to your specific needs. This pathway may also be helpful if your PCP has declined to prescribe.
Option 3: Telehealth Providers — Fastest Path
Telehealth platforms offer the fastest route to a Foundayo prescription. Many can evaluate and prescribe within 24–48 hours, with some offering same-day prescriptions. Telehealth is available nationwide and eliminates the need for an in-person office visit. Providers offering GLP-1 prescriptions include:
- Ro — online evaluation, prescription, and pharmacy fulfillment
- Hims — weight management program with GLP-1 prescribing
- MEDVi — specializes in oral and injectable GLP-1 options
- Found, Calibrate, and other weight management platforms
Telehealth visits typically cost $50–$150 for the consultation, and many platforms offer ongoing monthly subscriptions that include provider access, medication management, and check-ins.
Oral GLP-1 tablets now available — from $99/mo
Done with injections? MEDVi offers GLP-1 pills and tablets alongside injectables. Take a 60-second quiz to see your options.
See Oral GLP-1 Options →What to Bring to Your Appointment: Checklist
Whether you see your PCP, a specialist, or a telehealth provider, prepare the following:
- Current weight and height (or a recent BMI measurement — you can calculate BMI at CDC's BMI calculator)
- List of weight-related health conditions — hypertension, T2D, sleep apnea, joint problems, etc.
- Previous weight loss attempts — diets tried, exercise programs, behavioral counseling, prior medications (phentermine, orlistat, Contrave, etc.), and their outcomes
- Current medications — particularly important: statins, CYP3A4 inhibitors/inducers, oral contraceptives (Foundayo may reduce oral contraceptive efficacy), and any other diabetes medications
- Family history of thyroid cancer or MEN2 — this is a contraindication that your provider must screen for
- Insurance card or willingness to self-pay via LillyDirect
What Your Doctor Will Evaluate
During your appointment, expect your provider to assess:
- BMI calculation — confirmed measurement, not self-reported
- Blood pressure
- Basic metabolic panel — fasting glucose, HbA1c, lipid panel
- Thyroid history — personal or family history of medullary thyroid carcinoma (MTC)
- Kidney and liver function — standard screening before starting any new medication
- Pregnancy status — Foundayo is contraindicated in pregnancy; a pregnancy test may be required for women of childbearing potential
Contraindications: Who Should NOT Take Foundayo
Foundayo should not be prescribed to individuals with:
- Personal or family history of medullary thyroid carcinoma (MTC)
- Multiple endocrine neoplasia syndrome type 2 (MEN2)
- Known serious hypersensitivity to orforglipron or any inactive ingredient
- Pregnancy — discontinue Foundayo at least 2 months before planned conception
Getting Your Prescription Filled
Once prescribed, you have several options for filling your Foundayo prescription:
- LillyDirect — Lilly's direct-to-patient pharmacy. Free home delivery. Shipping began April 6, 2026. Most patients receive medication within 3–5 business days.
- Amazon Pharmacy — integrates with insurance and offers convenient delivery
- Retail pharmacies — CVS, Walgreens, and independent pharmacies are expanding Foundayo availability through April and May 2026. Stock may be limited initially.
For details on LillyDirect pricing and ordering, see our LillyDirect guide.
Timeline: How Fast Can You Start?
- Telehealth: Evaluation and prescription often same day. Medication ships within 1–2 business days via LillyDirect.
- PCP appointment: Typically 1–2 weeks to schedule. Prescription issued at the visit. PA may add 2–5 business days if insurance is involved.
- Specialist: Referral wait times vary (2–8 weeks depending on your area).
For most patients seeking the fastest path, telehealth combined with LillyDirect self-pay offers the shortest time from decision to first dose — often under 1 week.
What to Say to Your Doctor
If you are not sure how to start the conversation, here is a straightforward script you can adapt:
"I've been managing my weight for [X years] and have tried [diet changes, exercise, other medications — be specific]. My BMI is currently [number], and I also have [list conditions: high blood pressure, prediabetes, sleep apnea, etc.]. I've read about Foundayo, the new oral GLP-1 medication, and I'd like to discuss whether it's appropriate for me. I'm interested in starting treatment and would like to understand the titration schedule and any monitoring I'll need."
Being specific about your history and prior attempts demonstrates that you have done your research and are approaching weight management as a medical issue, which most providers appreciate. For dosing details, see our Foundayo dosing and titration guide.
Medical Disclaimer
Foundayo (orforglipron) is a prescription medication. This article is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before starting any new medication. Individual eligibility, dosing, and insurance coverage will vary. Do not take Foundayo if you have a personal or family history of medullary thyroid carcinoma or MEN2.