Foundayo (orforglipron) received FDA approval on April 1, 2026, and is now available by prescription across the United States. It's the first non-peptide oral GLP-1 pill for weight loss — a once-daily tablet you can take any time, with or without food. Here's exactly how to get it.
Availability Timeline
- April 1, 2026 — FDA approval; prescriptions accepted immediately
- April 6, 2026 — LillyDirect begins free home delivery
- April 8, 2026 — Amazon Pharmacy launches Foundayo with same-day delivery in select cities
- April–June 2026 — Retail pharmacies (CVS, Walgreens, etc.) and telehealth providers rolling out access
- July 1, 2026 — Medicare Part D coverage begins at $50/month for eligible beneficiaries
How to Get Foundayo: Step by Step
Foundayo requires a prescription — it cannot be purchased over the counter. Here's the fastest path:
1. Get a Prescription
You have three options:
- LillyDirect — Visit LillyDirect.com for an online clinician consultation. If approved, your prescription is filled and shipped directly.
- Telehealth providers — LifeMD, Ro, Hims & Hers, Found, and others now prescribe Foundayo. Online consultations typically take 15-30 minutes.
- Your doctor — Any licensed prescriber can write a Foundayo prescription. Bring up the medication at your next appointment or request a telehealth visit.
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See Oral GLP-1 Options →2. Choose Your Pharmacy / Delivery
| Channel | Speed | Notes |
|---|---|---|
| LillyDirect | 3-5 business days | Free shipping. Savings card applied automatically. Best for self-pay. |
| Amazon Pharmacy | Same-day in select cities | Accepts insurance. Manufacturer coupons applied at checkout. Nationwide 2-day delivery. |
| CVS / Walgreens / retail | Same day (if in stock) | Check availability first. May need to order. Insurance accepted. |
| Telehealth (Ro, LifeMD, etc.) | 2-5 days | Prescription + delivery bundled. Consultation fee may apply. |
3. Start Your Titration
Foundayo uses a 30-day titration schedule. Your doctor will start you at 0.8mg daily and increase every 30+ days:
0.8mg → 2.5mg → 5.5mg → 9mg → 14.5mg → 17.2mg (max)
Most patients reach their maintenance dose in 3-5 months. See our week-by-week side effects guide for what to expect at each dose level.
What Foundayo Costs in 2026
| Scenario | Monthly Cost |
|---|---|
| Commercial insurance + savings card | $25/month |
| Self-pay (0.8mg starting dose) | $149/month |
| Self-pay (2.5mg) | $199/month |
| Self-pay (5.5mg–17.2mg) | $299/month |
| Self-pay (lapsed 45+ days) | $349/month |
| Medicare Part D (from July 2026) | $50/month |
For a full breakdown of every savings option, see our Foundayo savings card guide and complete pricing guide.
Who Qualifies for Foundayo?
Foundayo is FDA-approved for adults with:
- Obesity — BMI ≥30
- Overweight — BMI ≥27 with at least one weight-related condition (high blood pressure, type 2 diabetes, high cholesterol, sleep apnea)
It's used alongside a reduced-calorie diet and increased physical activity. Foundayo should not be combined with other GLP-1 medications (Ozempic, Wegovy, Zepbound, Mounjaro, Rybelsus).
Switching from Another GLP-1 to Foundayo
Already on a GLP-1 medication? You can switch directly to Foundayo without a washout period in most cases:
- Zepbound → Foundayo — Lilly's recommended maintenance pathway. Our most popular guide.
- Ozempic → Foundayo — Start Foundayo the day after your last Ozempic injection.
- Wegovy → Foundayo — Same-day switch supported by ATTAIN-MAINTAIN trial data.
- Compounded semaglutide → Foundayo — With the FDA crackdown, this is the most affordable FDA-approved alternative.
Not sure which GLP-1 to choose? Compare Foundayo vs the Wegovy pill or browse all oral GLP-1 options.
Foundayo on Amazon Pharmacy
As of April 8, 2026, Amazon Pharmacy sells Foundayo with same-day delivery in select metro areas and nationwide 2-day delivery for Prime members. Amazon automatically applies manufacturer coupons at checkout, and has reported that GLP-1 medications are their largest savings category (over $200 million saved for customers to date).
To order via Amazon Pharmacy, you need a valid prescription from your doctor or telehealth provider. Amazon accepts most insurance plans.
Medicare Coverage (Starting July 2026)
Eli Lilly has committed to making Foundayo available at $50/month for eligible Medicare Part D beneficiaries starting July 1, 2026. This is separate from the Medicare GLP-1 Bridge program (which covers Wegovy and Zepbound). For full details, see our Medicare GLP-1 coverage guide.
Key Facts About Foundayo
- What it is: Orforglipron, a non-peptide small molecule GLP-1 receptor agonist
- How you take it: One pill daily, any time, with or without food
- Weight loss: 12.4% average body weight loss at the highest dose (ATTAIN-1 trial, 72 weeks)
- No injections, no refrigeration, no fasting
- Manufacturer: Eli Lilly (same company as Zepbound and Mounjaro)
For a deep dive, see our complete Foundayo medication profile.